Biotech Advisory
Precision advisory for biotech's hardest problems.
Specialist consultancy across payloads, antibody-drug conjugates, peptide conjugates, and outsourced synthetic chemistry campaigns.
Areas of Expertise
Payload Strategy & Optimisation
Deep expertise in cytotoxic and novel payload selection, linker chemistry, and SAR-driven optimisation. From first-in-class warhead identification through to candidate nomination, with rigorous attention to therapeutic index and manufacturability.
Antibody-Drug Conjugates
End-to-end ADC programme advisory — conjugation chemistry, DAR control, site-specific approaches, and analytical characterisation strategies. Experienced across both stochastic and site-specific platforms with multiple clinical-stage programmes.
Peptide Conjugates
Targeted peptide-drug conjugate design integrating receptor biology, peptide stability engineering, and conjugation site selection. Advisory spans early discovery through IND-enabling studies, with particular depth in GLP-1 and tumour-targeting vectors.
Outsourced Synthetic Chemistry
Strategic management of CRO and CDMO chemistry campaigns — from vendor selection and technical due diligence through to milestone governance and IP protection. Ensuring scientific rigour and programme continuity across distributed synthesis networks.
"The gap between scientific ambition and clinical reality is closed by those who understand both."
Ready to advance your programme?
Whether you are building a conjugate platform, evaluating a payload strategy, or structuring an outsourced chemistry campaign, Aklyva provides the scientific depth and strategic clarity your programme demands.